Multiple interaction partners for Cockayne syndrome proteins: Implications for genome and transcriptome maintenance
نویسندگان
چکیده
منابع مشابه
Interaction between the Cockayne syndrome B and p53 proteins: implications for aging
The CSB protein plays a role in the transcription coupled repair (TCR) branch of the nucleotide excision repair pathway. CSB is very often found mutated in Cockayne syndrome, a segmental progeroid genetic disease characterized by organ degeneration and growth failure. The tumor suppressor p53 plays a pivotal role in triggering senescence and apoptosis and suppressing tumorigenesis. Although p53...
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ژورنال
عنوان ژورنال: Mechanisms of Ageing and Development
سال: 2013
ISSN: 0047-6374
DOI: 10.1016/j.mad.2013.03.009